Blocking anti-aging enzyme makes cancer die of old age

“At the cellular level, aging and #cancer are two sides of the same coin. The mechanism that limits a cell’s lifespan can be slowed down, but that can turn them cancerous, as they divide unchecked. Now, scientists at EPFL have found a way to manipulate that mechanism to effectively turn off cancer’s immortality, letting it […]

Our Unneighborly Neighborhood: New Technique to Reveal Solar System’s Secrets

  The observable universe is a ginormous realm, whose 42.3 billion light year radius is riddled with galaxy filaments and voids. Suspended in one of the trillions of galaxies is an infinitesimal speck, a speck consisting of what humans may refer to as our neighborhood: the #solar system. Juxtaposed to the cosmic scale, the solar […]

Illuminating the Darkness? Primordial Black Holes Could be Elusive Dark Matter

Dark matter is one of the most accurately and least accurately named creatures in physics. The “dark” designation is not a mistake. Its noninteraction with any passing photons renders it inaccessible to optical telescopes and current scientific theories cannot yet illuminate its composition. And yet, precisely this lack of understanding is why Neil deGrasse Tyson […]

The Neurogenesis Debate

Written by Nicholi Avery On March 7 2018, a study was published in the highly esteemed journal Nature by an international team of scientists claiming that #neurogenesis starts to rapidly decline in the #human brain as early as 13 years old and becomes undetectable in adults.  This rocked the scientific community as there has been a long-established theory […]

The Origin of Life

Researchers have had a breakthrough in the central questions about #the origin of life. A collaboration of physicists and biologists in Germany has found a simple mechanism that might have enabled liquid droplets to evolve into living #cells in early Earth’s primordial soup. How did these first cells arise from primitive precursors? What were those […]

A Clinical-Grade Implant May Cure Blindness

Written by Nicholi Avery Edited by Carla Parsons A clinical-grade retinal implant made of human #embryonic stem cell (#hESC)–derived RPE grown on a synthetic substrate has been developed by Kashani and team. The progressive binding disease that causes loss of the retinal pigment epithelium (RPE) of the eye is known as #Non-neovascular age-related macular degeneration […]

Researchers discover switch that converts blood vessels to blood stem cells!

A team of scientists in the UK and Italy has discovered a switch that instructs #blood vessel cells to become blood #stem cells during #embryonic development in mice. These findings could aid research into new blood cell creation for #transplants. Using single-cell technology, researchers from the Wellcome Sanger Institute in Cambridge and the European Molecular Biology Laboratory […]

Harvard Rewinds the Biological Clock

Investigators at Harvard Medical School have identified the key cellular mechanisms behind vascular aging and its effects on muscle health, and they have successfully reversed the process in animals. The scientists used a chemical compound that’s an NAD+ booster called NMN which plays a critical role in repairing cellular DNA as well as maintaining cell […]

The Root of All Cruelty?

A recent episode of the dystopian television series “Black Mirror” begins with a soldier hunting down and killing hideous humanoids called roaches. It’s a standard science-fiction scenario, man against monster, but there’s a twist: it turns out that the soldier and his cohort have brain implants that make them see the faces and bodies of […]

Elon Musk – Artificial Intelligence, Neuralink & New Forms of Government on Mars

#Elon Musk discussed his concerns about #artificial intelligence and his hope for forming a symbiosis with AI through his #Neuralink company at SXSW on March 11th, 2018. Musk also spoke about the prospects for complete #renewable energy production, #space-based internet and the new types of government that could appear on #Mars.

Targeting levels of specific protein could improve memory in aging, reduce symptoms of PTSD

A neural circuit mechanism involved in preserving the specificity of memories has been identified by investigators from the Massachusetts General Hospital (MGH) Center for Regenerative Medicine and the Harvard Stem Cell Institute (HSCI). They also identified a genetic “switch” that can slow down #memory generalization — the loss of specific details over time that occurs […]

Astronomers peer inside the mysterious void of our Cosmos

There’s a lot we can learn by looking at all those voids making #space between galaxies – and now, for the first time, #astronomers have used a new method to peer inside these mysterious pockets of #nothingness. Voids in space are due to the expansion of the Universe – this results in a web of […]

The Limits of Neuroplasticity in the Brain

New research shows that the #brain‘s #neuroplasticity isn’t as flexible as previously thought. One of the brain’s mysteries is how exactly it reorganizes new #information as you learn new tasks.  The standard to date was to test how neurons learned new behavior one #neuron at a time. Carnegie Mellon University and the University of Pittsburgh […]

Team develops 3-D tissue model of a developing human heart

The #heart is the first organ to develop in the womb and the first cause of concern for many parents. For expecting mothers, the excitement of pregnancy is often offset by anxiety over medication they require. Parents and doctors often have to consider the mother’s health as well as the potential risk regarding how medication […]

New therapeutic gel shows promise against cancerous tumors!

Scientists at the UNC School of Medicine and NC State have created an injectable gel-like scaffold that can hold combination #chemo-immunotherapeutic drugs and deliver them locally to tumors in a sequential manner. The results in animal models so far suggest this approach could one day ramp up therapeutic benefits for patients bearing tumors or after […]

IMPLICATIONS OF THE BPF LARGE MAMMAL BRAIN PRESERVATION PRIZE

A special thank you to #Keith Wiley for allowing me to post this article in full on our blog.  To see more awesome posts by Keith Wiley please check out the BPF blog: here. He is also the author of a book titled A Taxonomy and Metaphysics of Mind Uploading (2014)  Keithwiley.com A FOLLOW UP TO THE […]

Human Skeletal Muscle Aging and Mutagenesis

Study based upon human skeletal muscle aging, mutagenesis, and the role of #satellite cells “A more comprehensive understanding of the interplay of stem cell–intrinsic and extrinsic factors will set the stage for improving cell therapies capable of restoring tissue homeostasis and enhancing muscle repair in the aged.” Human aging has multiple effects on the human […]

Australia Is Set to Become The First Country to Completely Eliminate One Type of Cancer

The International Papillomavirus Society has announced that Australia could become the first country to eliminate cervical cancer entirely. According to a new study, Australia’s efforts to distribute a human papillomavirus (HPV) vaccine for free in schools have been a resounding success. The sexually transmitted infection causes 99.9 percent of cases of #cervical cancer. In 2007, the Australian federal […]

Insights into the Neurobiology of Death

A recent study gives insight into the #neurobiology of dying.  Before the process of dying neurologists closely monitored patients with devastating #brain injuries following Do Not Resuscitate-Comfort Care orders.  This gave key insights into the mechanisms and timing of events in the brain and the circulatory system  during the dying process. The objective of emergency […]

Enzymes and Cognitive Decline

Enzymes play an important role in cognitive function.  Enzymes are biological catalysts.  They’re responsible for accelerating chemical reactions. What role do enzymes play in #aging and cognitive function?  According to new research in laboratory mice by UC San Francisco scientists have discovered that loss of an #enzyme that modifies gene activity to promote brain regeneration […]

Biotech Company Regenerates Tendons, Hair and Skin.

In a pre-clinical study a Canadian regenerative medicine biotech company RepliCel Life Sciences successfully regenerated skin and stimulated hair growth in pigs with burns and abrasions therapy: resulting in scarless healing, growth of hair follicles, complete wound coverage, and the progressive regeneration of all skin layers and tendons. The company focuses on the development of a cell […]

Our Individuality is Not Determined by Our Genes

Put 50 newborn worms in 50 separate containers, and they’ll all start looking for food at roughly the same time. Like members of other species, microscopic C. elegans roundworms tend to act like other individuals their own age. It turns out that the innate system that controls age-appropriate #behavior in a developing worm is not […]

Evolution: What the Fossils Say

Is evolution a fact? How do the claims of creationists stack up against the fossil record and the actual science? Dr. Donald Prothero presents the evidence in a presentation based on his 2007 book (and more recent findings). Prothero is a paleontologist, geologist, author and science educator. He holds a Ph.D in geological sciences from […]

Neurobiological Changes Explain How Mindfulness Meditation Improves Health

Over the past decade, #mindfulness #meditation has been shown to improve a broad range of #health and disease outcomes, such as slowing HIV progression and improving healthy #aging. Yet, little is known about the #brain changes that produce these beneficial health effects. New research from Carnegie Mellon University provides a window into the brain changes […]

It Turns Out, Andromeda is Younger Than Earth… Sort Of – Universe Today

Since ancient times, astronomers have looked up at the night sky and seen the Andromeda galaxy. As the closest galaxy to our own, scientists have been able to observe and scrutinize this giant spiral galaxy for millennia. By the 20th century, astronomers realized that Andromeda was the Milky Way’s sister galaxy and was moving towards […]

My Journey With Cancer and the Hope for the Future

I would like to share a story.  A story about sadness, depression, anger, and frustration.  But most of all this is my personal story about triumphing over the death sentence of #cancer.  I hope this story will give others who went through and are going through hope for the future. My story started about 4 […]

We Read This 800-Page Report on the State of Longevity Research So You Don’t Have To

The longevity field is bustling but still fragmented, and the “silver tsunami” is coming. That is the takeaway of The Science of Longevity, the behemoth first volume of a four-part series offering a bird’s-eye view of the longevity industry in 2017. The report, a joint production of the Biogerontology Research Foundation, Deep Knowledge Life Science, […]

Scientists find key proteins control risk of osteoarthritis during aging

Now, a study from scientists at The Scripps Research Institute (TSRI) explains why the risk of osteoarthritis increases as we #age and offers a potential avenue for developing new therapies to maintain healthy #joints. The study’s findings suggest that #FOXO proteins are responsible for the maintenance of healthy cells in the #cartilage of our joints. “We discovered that […]

Study Finds that Fasting for 72 Hours Can Regenerate the Entire Immune System – Awareness Act

There has long been controversy surrounding the potential benefits or hazards of fasting. On one hand, supporters of fasting point to the many benefits that they claim fasting provides. This includes promoting weight loss, normalizing insulin sensitivity, lowering triglyceride levels in the body and slowing the signs of aging. There are a number of different […]

Nanorobots Programmed to Destroy a Tumor!

They successfully test a system in mice that fights #cancer by letting the tumor starve without attacking healthy cells. New ways to fight cancer The films Fantastic Voyage (1966) and The Imaginary Chip (1987) imagined what it would be like to put a miniature manned submarine inside a person capable of traveling through the bloodstream to repair the damaged tissues of […]