How do you combat fears that people will be devastated, or perhaps give up trying to be healthy, if they learn they’re at elevated risk for a disease?
Do we have everybody practicing a healthy lifestyle? No. I don’t want to diminish the importance of it, but a lot of people have the healthiest lifestyle in the world and they get struck by things like autoimmune diseases and Alzheimer’s.
We’re going to make darn sure that we have people included of all socioeconomic classes.
We want to have all different ways to identify people and get them enrolled – going to people’s homes to enroll elderly people, enrolling people at blood banks where people volunteer to sell their blood.
We need to develop treatments that are far more likely to succeed in a smaller swath of people. Today, the thing you get most out of a sequence are these “Variants of unknown significance.” The more people that are sequenced, the fewer of these there will be.
One little study – 5,000 people, predominantly Caucasian – had more impact than any other study ever done about the heart.