By taking a different approach researchers at Houston Methodist made a surprising discovery leading to the development of technology with the ability to rejuvenate human cells.
Cooke studied cells from children with progeria, a rare condition marked by rapid aging that usually robs them of the chance to live beyond their early teens.
We wanted to do something that would improve the children’s quality of life and potentially allow them to live longer, so we set about studying their cells and seeing if we could improve the cell function.
“What we’ve shown is that when we reverse the process of the telomere shortening in the cells from these children and lengthen them, it can reverse a lot of the problems associated with aging.
Essentially, they gave the cells the information they needed to extend the telomere via an RNA delivery system and let the cells do the rest. “We were not expecting to see such a dramatic effect on the ability of the cells to proliferate.
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