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Sharon Terry: Science didn’t understand my kids’ rare disease until I decided to study it

Meet Sharon Terry, a former college chaplain and stay-at-home mom who took the medical research world by storm when her two young children were diagnosed with a rare disease known as pseudoxanthoma elasticum (PXE). In this knockout talk, Terry explains how she and her husband became citizen scientists, working midnight shifts at the lab to find the gene behind PXE and establishing mandates that require researchers to share biological samples and work together.

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Genetic Struggles Within Cells May Create New Species | Quanta Magazine

Mitonuclear conflict — a struggle between the genes in a cell’s nucleus and its mitochondria — might sometimes split species in two.

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In Newly Created Life-Form, a Major Mystery | Quanta Magazine

Scientists have created a synthetic organism that possesses only the genes it needs to survive. But they have no idea what roughly a third of those genes do.

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Gold nanoparticle used to replace virus in new CRISPR approach

(Phys.org)-A team of researchers from the University of California and the University of Tokyo has found a way to use the CRISPR gene editing technique that does not rely on a virus for delivery. In their paper published in the journal Nature Biomedical Engineering, the group describes the new technique, how well it works and improvements that need to be made to make it a viable gene editing tool.

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Nanotechnology Now – Press Release: ‘CRISPR-Gold’ fixes Duchenne muscular dystrophy mutation in mice

Scientists at the University of California, Berkeley, have engineered a new way to deliver CRISPR-Cas9 gene-editing technology inside cells and have demonstrated in mice that the technology can repair the mutation that causes Duchenne muscular dystrophy, a severe muscle-wasting disease. A new study shows that a single injection of CRISPR-Gold, as the new delivery system is called, into mice with Duchenne muscular dystrophy led to an 18-times-higher correction rate and a two-fold increase in a strength and agility test compared to control groups.

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Two-part system turns stem cells into whatever you want

Whether using embryonic or adult stem cells, coercing these master cells to convert to the desired target cell and reproduce flawlessly is difficult. Now an international team of researchers has a two-part system that can convert the cells to the targets and then remove the remnants of that conversion, leaving only the desired DNA behind to duplicate.

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A Genetic Oddity May Give Octopuses and Squids Their Smarts

Unlike other organisms, coleoid cephalopods make extensive use of RNA editing, which could slow their evolution but may make their behavior more complex than other invertebrates.

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These Are The 11 Extinct Animals on the List to Be Brought Back to Life

The Long Now Foundation has created a list of extinct species that it believes we should consider resurrecting via DNA and other modern technologies. Some argue that this would amount to “playing God,” but the reintroduction of some of these species could revitalize natural habitats and increase flora and fauna.

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Scientists say all the world’s data can fit on a DNA hard drive the size of a teaspoon

Even though it’s looking increasingly likely that humanity will find a way to wipe itself off the face of the Earth, there’s a chance that our creative output may live on. Servers, hard drives, flash drives, and disks will degrade (as will our libraries of paper books, of course), but a group of researchers at the Swiss Federal Institute…

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Scientists say all the world's data can fit on a DNA hard drive the size of a teaspoon

Even though it’s looking increasingly likely that humanity will find a way to wipe itself off the face of the Earth, there’s a chance that our creative output may live on. Servers, hard drives, flash drives, and disks will degrade (as will our libraries of paper books, of course), but a group of researchers at the Swiss Federal Institute…