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In Newly Created Life-Form, a Major Mystery | Quanta Magazine

Scientists have created a synthetic organism that possesses only the genes it needs to survive. But they have no idea what roughly a third of those genes do.

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Assay of nearly 5,000 mutations reveals roots of genetic splicing errors

Brown biologists have developed a new system, described in Nature Genetics, that identified and tracked hundreds of genetic variations that alter the way DNA is spliced when cells make proteins, often leading to disease.