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Two Compounds Revealed to Slow Age-Induced Degeneration

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Researchers from the Virginia Tech Carilion Research Institute and colleagues have discovered the anti-aging effects of two compounds.

The former, known as resveratrol, has been previously regarded for its health benefits and has even been called “An elixir of youth.” The latter, a drug called metformin, has also been researched for its anti-cancer effects.

“Gait, balance issues, and impaired motor coordination contribute to health problems, accidents, lack of mobility, and a lower quality of life. We work on identifying molecular changes that slow down motor deficits that occur with aging. I believe that we are getting closer to tapping into mechanisms to slow age-induced degeneration of neuronal circuits.”

The team found that resveratrol can preserve muscle fibers and protect synapses from aging’s crippling effects. The team paid particular attention to how resveratrol affected synapses called neuromuscular junctions. “In wine, resveratrol is in such small amounts you could not drink enough of it in your life to have the benefits we found in mice given resveratrol,” Valdez explained.

As for resveratrol, the researchers plan to further study what exactly allows for these neuroprotective effects.


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Post Author: Carla Parsons

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