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Tideglusib stimulates stem cells in the pulp of teeth, promoting new dentine production and natural tooth repair. Developed for and trialled to treat Alzheimer’s disease, the drug also happens to promote the natural tooth regrowth mechanism, allowing the tooth to repair cavities. Tideglusib works by stimulating stem cells in the pulp of teeth, the source of new dentine. Dentine is the mineralized substance beneath tooth enamel that gets eaten away by tooth decay. Teeth can naturally regenerate dentine without assistance, but only under certain circumstances. The tooth can only regrow a very thin layer naturally-not enough to repair cavities caused by decay, which are generally deep.

He added, “The simplicity of our approach makes it ideal as a clinical dental product for the natural treatment of large cavities, by providing both pulp protection and restoring dentine.”


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